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. 2022 May 11;9:854554. doi: 10.3389/fcvm.2022.854554

Table 4.

Showing optical properties and OCT image interpretation of various atherosclerotic plaque morphologies.

Tissue Optical properties Imae
Backscatter Attenuation
Lipid Low High Anatomic border with fibrous layer cannot be made out due to high backscattering. But then light attenuates much faster. So, lipid pool is progressively dark (Figure 1B)
Fibrous High Low Bright signal rich homogenous appearance (Figure 1C)
Calcified tissue Low Low Signal poor region with sharp boundaries between calcified and fibrous tissue (Figures 1D–F)
Thin cap fibrous atheromas (TCFA) • Cap–High
• Core–low
• Cap–Low
• Core–High
Bright and signal rich fibrous cap followed by signal poor area of lipid pool with cap thickness <65 μm. TCFAs are more prone for plaque rupture (Figure 1G)
Red thrombus High High Intraluminal mass and casts a shadow on the vessel walls due to high attenuation of RBCs (Figure 1H)
White thrombus High Low Intraluminal mass with no attenuation (Figure 1I)
Macrophages High High Bright spots or bands at border between fibrous cap and lipid core casting shadow behind it (Figure 1J)
Cholesterol crystal High Low Thin & linear structure in the plaque (Figure 1K)