Table 2.
CMR strain and LGE data of the study population.
| HCM (n = 57) | HHD (n = 45) | * P | Healthy (n = 68) | § P | |
|---|---|---|---|---|---|
| GRS (%)# | 21.18 ± 7.52 | 14.56 ± 7.46 | <0.001 | 32.43 ± 6.09 | <0.001 |
| GCS (%)# | −13.34 ± 3.52 | −10.11 ± 4.13 | <0.001 | −18.66 ± 2.18 | <0.001 |
| GLS (%)# | −9.49 ± 3.06 | −9.34 ± 3.76 | 0.973 | −17.60 ± 1.57 | <0.001 |
| GRS rate (1/s)# | 1.27 ± 0.53 | 0.89 ± 0.44 | <0.001 | 1.64 ± 0.42 | <0.001 |
| GCS rate (1/s)# | −0.83 ± 0.28 | −0.64 ± 0.25 | 0.008 | −0.95 ± 0.38 | <0.001 |
| GLS rate (1/s)# | −0.61 ± 0.21 | −0.55 ± 0.26 | 0.428 | −0.91 ± 0.15 | <0.001 |
| BRS (%)# | 24.12 ± 8.21 | 15.25 ± 7.88 | <0.001 | 34.45 ± 6.95 | <0.001 |
| BCS (%)# | −14.73 ± 3.61 | −10.41 ± 4.31 | <0.001 | −19.26 ± 2.38 | <0.001 |
| BLS (%)# | −15.93 ± 4.51 | −13.55 ± 5.02 | 0.039 | −22.34 ± 2.87 | <0.001 |
| MRS (%)# | 19.90 ± 7.83 | 13.77 ± 8.27 | <0.001 | 31.12 ± 6.73 | <0.001 |
| MCS (%)# | −12.89 ± 3.76 | −9.70 ± 4.68 | 0.001 | −18.28 ± 2.52 | <0.001 |
| MLS (%)# | −6.69 ± 4.38 | −7.89 ± 3.97 | 0.323 | −15.19 ± 2.86 | <0.001 |
| ARS (%)# | 22.70 ± 12.62 | 18.24 ± 10.14 | 0.124 | 35.25 ± 11.04 | <0.001 |
| ACS (%)# | −13.26 ± 5.37 | −11.73 ± 4.79 | 0.216 | −19.10 ± 3.58 | <0.001 |
| ALS (%)# | −7.96 ± 5.52 | −8.14 ± 4.57 | 0.982 | −14.98 ± 3.31 | <0.001 |
| Torsion (deg/cm)# | 1.79 ± 0.69 | 1.23 ± 0.65 | <0.001 | 1.45 ± 0.71 | <0.001 |
| LGE (%)pounds | 7.4 (2.4, 13.9) | 4.0 (1.9, 7.5) | 0.040 | 0 | <0.001 |
| LGE Segment 7 (%)pounds | 4.4 (1.0, 14.5) | 1.0 (0.2, 4.1) | 0.001 | 0 | <0.001 |
| LGE Segment 8 (%)pounds | 4.6 (0.8, 14.7) | 0.7 (0.2, 3.5) | 0.001 | 0 | <0.001 |
| LGE Segment 9 (%)pounds | 4.5 (1.3, 11.3) | 1.2 (0.5, 3.7) | 0.001 | 0 | <0.001 |
| LGE mIVS (%)pounds | 5.4 (1.5, 15.9) | 1.3 (0.4, 3.4) | <0.001 | 0 | <0.001 |
*
P is for HCM vs. HHD.
§
P is for HCM and HHD patients vs. healthy volunteers.
#
Data are means ± standard deviation.
poundsData are medians with interquartile range. P < 0.05 is considered to indicate statistical significance. CMR, cardiovascular magnetic resonance; GRS, global radial strain; GCS, global circumferential strain; GLS, global longitudinal strain; BRS, basal radial strain; BCS, basal circumferential strain; BLS, basal longitudinal strain; MRS, mid radial strain; MCS, mid circumferential strain; MLS, mid longitudinal strain; ARS, apical radial strain; ACS, apical circumferential strain; ALS, apical longitudinal strain; LGE, late gadolinium enhancement; mIVS, mid interventricular septum.