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. 2022 May 23;12(5):e059994. doi: 10.1136/bmjopen-2021-059994

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Longitudinal trajectory of IgG-S antibody levels following completed BNT162b2 vaccination by prior infection status and age. Multivariable-adjusted longitudinal trajectories are shown for individuals with a history of prior COVID-19 infection and for those without prior COVID-19 infection, including an interaction for age (above vs below median cohort age). Longitudinal estimates with 95% confidence limits (shaded areas) are adjusted for sex and hypertension.