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. 2022 May 11;10:884412. doi: 10.3389/fcell.2022.884412

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Copyright © 2022 Gong, Wang and Shao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representation of biological functions of NOX4 in cancer. JAK2, Janus kinase 2; ASK1, apoptosis signal-regulating kinase 1; ANGPTL4, Angiopoetin-like 4; CAFs, cancer-associated fibroblasts; EMP1, epithelial membrane protein 1; GLUT1, glucose transporter 1; HK2, hexokinase 2; PKM2, pyruvate kinase isoform 2; LDHA, lactate dehydrogenase A.