Table 1.
Characteristics and Clinical Features of COVID-19 Patients in ICU.
| Characteristics of patients (n = 470) | |
|---|---|
| Demographics | |
| Age (years), median (IQR) | 66.0 (56.0-76.0) |
| Male, n (%) | 301 (64.0) |
| Comorbid conditions | |
| Hypertension, n (%) | 234 (49.8) |
| Diabetes Mellitus, n (%) | 154 (32.8) |
| Coronary artery disease, n (%) | 121 (25.7) |
| Solid tumor, n (%) | 68 (14.5) |
| Neurological disorders, n (%) | 41 (8.7) |
| Chronic obstructive pulmonary disease, n (%) | 39 (8.3) |
| Hematologic malignancy, n (%) | 30 (6.4) |
| End stage renal disease, n (%) | 27 (5.7) |
| Rheumatologic diseases, n (%) | 22 (4.7) |
| Other chronic pulmonary diseases, n (%) | 19 (4.0) |
| Moderate/severe liver failure, n (%) | 8 (1.7) |
| Previous use of beta lactam antibiotics, n (%) | 282 (60.0) |
| Previous use of macrolides, n (%) | 73 (15.5) |
| Diagnostic method for COVID-19 | |
| PCR positivity, n (%) | 414 (88.1) |
| Typical features on CT, n (%) | 453 (96.4) |
| Characteristics in ICU | |
| Tracheal intubation, n (%) | 352 (74.9) |
| Presence of central venous catheter, n (%) | 354 (75.3) |
| Presence of urinary catheter, n (%) | 450 (95.7) |
| Renal failure in ICU, n (%) | 180 (38.3) |
| Development of bloodstream infection, n (%) | 179 (38.1) |
| APACHE II score on admission, median (IQR) | 18.0 (14.0-24.0) |
| SOFA score on admission, median (IQR) | 5.0 (4.0-7.0) |
| Laboratory results on admission to ICU | |
| WBC (x10−3/mm3) | 9.7 (6.6-13.9) |
| Lymphocyte (x10−3/mm3) | 0.6 (0.4-0.8) |
| Platelet (x10−3/mm3) | 218.2 (159.1-320.0) |
| C-reactive protein (mg/L) | 108.0 (57.0-186.3) |
| Procalcitonin (ng/mL) | 0.32 (0.11-0.93) |
| Lactate dehydrogenase (U/L) | 521.5 (385.8-707.0) |
| Length of stay before ICU admission (day), median (IQR) | 4.0 (1.0-7.0) |
| Length of stay in ICU (day), median (IQR) | 10.0 (6.0-16.0) |
| Length of mechanical ventilation, median (IQR) | 5.0 (0.0-11.0) |
| Total length of stay in hospital (day), median (IQR) | 14.0 (11.0-20.3) |
| Final outcome, n (%) | |
| Discharge from ICU | 190 (40.4) |
| Death in ICU | 280 (59.6) |
PCR: Polymerase chain reaction, CT: Computed tomography, APACHE II: Acute Physiology and Chronic Health Evaluation, SOFA: Sequential Organ Failure Assessment, ICU: Intensive care unit.