Figure 14.

A distinctive hybrid system based on zeolitic imidazolate framework (ZIF) for synergistic photodynamic therapy and chemotherapy of endophthalmitis. a) Schematic illustration of constructed hybrid system ZIF‐8‐polyacrylic acid (ZIF‐8‐PAA)‐methylbenzene blue (MB)@silver nanoparticles (AgNPs)@vancomycin (Van)/NH‐PEG (ZPMAVP) for endophthalmitis treatment by synergistic chemotherapy and photodynamic therapy. b,c) Photographs and slit lamp micrographs of endophthalmitis resulted from Staphylococcus aureus (b) and methicillin‐resistant staphylococcus aureus (MRSA) (c) after treatment with three groups of PBS, Van, and ZPMAVP nanoparticles + laser (202 mW cm⁻²) at 1, 3, and 7 days, respectively. Reproduced with permission.^{[ 112 ]} Copyright 2019, Wiley‐VCH.