TABLE 2A.

Comparison of Z-score between baseline and after unilateral deep brain stimulation of the globus pallidus internus (GPi-DBS) by brain perfusion Single Photon Emission Computed Tomography (SPECT).

Location*	Change in pre- and post-op CBF	Z-score		p	Normalization in post-op CBF
		Pre-op	Post-op
<Good responders>
Ipsilateral transverse temporal	↓	–0.304	0.154	0.03	Yes
Contralateral premotor	↑	0.344	0.026	0.03	Yes
Ipsilateral cingulate	↓	0.229	0.475	0.04	Not
Contralateral primary auditory**	↑	0.130	–0.049	0.04	Yes
Contralateral inferior parietal	↑	0.641	0.373	0.045	Yes
<Poor responders>
Ipsilateral subcallosal	↑	–0.271	–0.842	0.01	Not
Ipsilateral inferior temporal	↓	–0.069	0.305	0.01	Not
Contralateral fusiform	↑	0.023	0.123	0.01	Not
Contralateral orbital	↑	–0.106	0.497	0.02	Not
Ipsilateral globus pallidus	↓	–0.212	0.426	0.02	Not
Ipsilateral substantia nigra	↓	–0.228	0.476	0.03	Not
Ipsilateral anterior cingulate	↓	–0.194	–0.456	0.03	Not
Contralateral paracentral lobule	↑	0.117	–0.166	0.03	Not
Ipsilateral orbital	↑	–0.251	–0.608	0.03	Not
Ipsilateral nucleus ruber	↓	0.021	0.575	0.03	Not

Patients were divided into good and poor responders in changes of Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) part III total scores after surgery. *Only locations with significant changes in post-op CBF were extracted. **Primary auditory overlaps anatomically with frontal lobes. ↑: increased CBF, ↓: decreased CBF.