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. 2022 May 25;13(5):498. doi: 10.1038/s41419-022-04961-z

Fig. 5. Effect of raloxifene on ACE2-S protein interaction.

Fig. 5

A SPR experiments showed that raloxifene does not interfere with either S binding to immobilized ACE2 (left panel) or with ACE2 binding to immobilized S (right panel). Solutions were injected in triplicate; black lines show the sensorgrams with the proteins alone, while red lines show the sensorgrams with the proteins preincubated with raloxifene. B TR-FRET ACE2-SpikeS1 interaction assay showed that raloxifene is not able to interfere with the protein binding.