Table 4.
Neutralization antibodies titer of the vaccinated mice in comparison to control mice
|
Vaccinated mice groups Type of vaccine |
Neutralization titer/day post-vaccination | |||||||
|---|---|---|---|---|---|---|---|---|
| 0 d | 7d | 14d * (2nd injection) |
21d | 28d (3rd injection) | 35d | 38d (4th injection) | 42d | |
|
CVMW without KLH (3 mice) |
< 1:10 | 1:40 | 1:40 | 1:80 | 1:80 | 1:160 | 1:267 | 1:320 |
|
CVMW conjugated with KLH (3 mice) |
< 1:10 | 1:20 | 1:33 | 1:40 | 1:40 | 1:80 | 1:107 | 1:133 |
|
Control (3 mice) |
< 1:10 | < 1:10 | < 1:10 | < 1:10 | < 1:10 | < 1:10 | < 1:10 | < 1:10 |
NAb value = reciprocal the dilution of serum that neutralize 3.5 log 10 of sars-cov2 virus