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. 2022 May 25;13(5):500. doi: 10.1038/s41419-022-04964-w

Fig. 3. Paclitaxel-C5aR1 intracellular pathway.

Fig. 3

Quantification of the expression of phosphorylated and total forms of NFκB (A), c-Jun (B), c-Fos (C), p38 MAPK (D) and ERK3/MAPK6 (E) in differentiated F11 cells following paclitaxel (PAC) treatment evaluated by western blot analysis (F). F11 cells were treated for 24 h with PAC (10 nM) and DF3966A (10 µM). ***P < 0.0005; *P < 0.05 vs CTR; +++P < 0.0005 vs paclitaxel. Data are mean ± SEM of n = 3 different experiments.