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. 2022 May 25;13(5):500. doi: 10.1038/s41419-022-04964-w

Table 1.

Selected potential paclitaxel targets and their predicted affinity.

Target Predicted affinity
TLR2_HUMAN High
NK1R_HUMAN High
EDNRB_HUMAN High
EGFR_HUMAN High
C5AR1_HUMAN High
EDNRA_HUMAN High
PAR2_HUMAN Low
C5AR2_HUMAN Low
AA2BR_HUMAN Low
RET_HUMAN Low
CRFR2_HUMAN Low
TNR1A_HUMAN Low
S1PR1_HUMAN n.b
PAR1_HUMAN n.b
KIT_HUMAN n.b
ADRB2_HUMAN n.b
TLR8_HUMAN n.b
LPAR1_HUMAN n.b
TGFR2_HUMAN n.b
DDR1_HUMAN n.b
NTR1_HUMAN n.b
PTAFR_HUMAN n.b
C3AR_HUMAN n.b
PE2R2_HUMAN n.b
ACM3_HUMAN n.b
PE2R3_HUMAN n.b
PE2R4_HUMAN n.b

Selected potential paclitaxel targets and their sources with the corresponding in silico classification based on docking experiments. n.b. are non-bound protein.