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. 2022 May 20;8(5):e09503. doi: 10.1016/j.heliyon.2022.e09503

Figure 2.

Figure 2

Dapagliflozin-induced vasodilation is not mediated by NO signaling. (A) Original traces illustrating the modulation of dapagliflozin (Dapa, 100 μM)-induced vasorelaxation. Concentrations of L-NNA, ODQ, and KT5823 used were 10 μM, 10 μM and 1 μM, respectively. (B) Mean data comparing Dapa-induced mesenteric artery relaxation with or without the modulators, n = 4.