Figure 6.
Relative tumor growth curve (A) and average body weight (B) of 4T1 tumor-bearing mice after various treatments indicated at an equivalent dosage of MB in 18 days. Corresponding average tumor weights (C) and representative tumor photographs (D) of 4T1 tumor-bearing mice after treatments on 18th day. Intratumoral GSH level (E) and ROS generation (F) isolated from 4T1 tumor- bearing mice with different treatments. (G) The H&E and TUNEL staining of tumor sections after treatments on 18th day. Scale bar: H&E staining 400 μm; TUNEL staining 100 μm. (+) and (-) refer to the treatment with or without NIR irradiation, respectively. Results are described as mean ± SD, n = 6. *p < 0.05, **p < 0.01, and ***p < 0.001.