Table 4.
Time 2 Correlations Between Default Mode Network Connectivity, Cognitive Function, and Clinical Variables
| Behavioral/Clinical variable | DMN variable | Connectivity variable | r | p (uncorrected) |
|---|---|---|---|---|
| Breast cancer | ||||
| Interference recall | LSOF-RANG | Centrality | −0.361 | 0.029 |
| LMEOF-LRECT | FA | −0.545 | 0.015 | |
| COWA | RSOF-LRECT | FA | −0.785 | 0.0002 |
| Number of chemotherapy cycles | RMESF-LMEOF | Centrality | 0.667 | <0.0001 |
| RMESF-LRECT | Centrality | 0.361 | 0.030 | |
| RMESF-LSOF | Centrality | 0.333 | 0.042 | |
| RMESF-RRECT | Centrality | 0.357 | 0.031 | |
| Radiation therapy | RSOF-RANG | Centrality | 0.376 | 0.024 |
| RPCING-RPCUN | Centrality | −0.393 | 0.019 | |
| RMESF-LRECT | Centrality | −0.325 | 0.046 | |
| LSOF-LMEOF | FA | −0.533 | 0.017 | |
| Hormone blockade therapy | RMESF-RPCING | Centrality | −0.348 | 0.035 |
| LPCUN-RPCUN | Centrality | −0.364 | 0.028 | |
| RANG-LRECT | Centrality | −0.319 | 0.049 | |
| Controls | ||||
| Interference recall | LRECT-RMESF | Centrality | −0.255 | 0.049 |
| LSOF-RPCUN | Centrality | 0.276 | 0.036 | |
| Trail 1 | LSOF-RPCUN | Centrality | 0.285 | 0.032 |
| COWA | LSOF-LMEOF | FA | −0.435 | 0.023 |
Only significant (p < 0.05) correlations are shown.
DMN, default mode network; FA, fractional anisotropy; L/RMEOF, left/right medial orbital frontal; L/RPCUN, left/right precuneus; L/RRECT, left/right rectus gyrus; L/RSOF, left/right superior orbital frontal; RANG, right angular gyrus; RMESF, right medial superior frontal; RPCING, right posterior cingulate.