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. 2022 Mar 27;9(15):2105336. doi: 10.1002/advs.202105336

Figure 3.

Figure 3

High‐lonely men showed decreased right amygdala habituation (MNIxyz: 34, 2, −22, F (1,75) = 12.72, p FWE = 0.04, n = 79; A) to fearful faces in contrast to high‐lonely women and this pattern was reversed in low‐lonely individuals. In addition, increased coupling between the right amygdala (red cluster) as the seed region and left superior parietal lobule (blue cluster; MNIxyz: −34, −52, −58, k (1,75) = 108, p FWE = 0.01; n = 79; B) was observed during fear habituation in high‐lonely men compared to high‐lonely women, whereas this pattern was again reversed in low‐lonely individuals. Coordinates are in MNI space. Error bars show the standard error of the mean (SEM). Abbreviations: L, left; R, right. P‐values were calculated by mixed design ANOVAs with the fixed factors sex and loneliness and post hoc two‐sample t‐tests. * p < 0.05.