Table 5.
Risk factors for weaning failure
| Variable | NO. of failure/total(%) | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|
| Unadjusted OR | 95%CI | P | Adjusted OR | 95%CI | P | ||
| MPV, fl | |||||||
| ≤ 11.3 | 24/206(11.7) | ||||||
| > 11.3 | 30/55(54.5) | 9.1 | 4.609–17.969 | 0.000 | 8.101 | 3.622–18.117 | 0.000 |
| Leukocytes, × 10.9/L | |||||||
| ≤ 8.9 | 15/111(13.5) | ||||||
| > 8.9 | 39/142(27.5) | 2.445 | 1.364–5.053 | 0.003 | 3.495 | 1.498–8.154 | 0.004 |
| CRP, mg/L | |||||||
| ≤ 67 | 23/159(14.5) | ||||||
| > 67 | 31/102(30.4) | 2.582 | 1.401–4.756 | 0.000 | 2.121 | 0.987–4.561 | 0.054 |
Multivariate logistic regression was performed with covariates including APACHE II score, IMV duration prior to weaning, postoperation, PaCO2, PaO2/FiO2, SPO2, SBP, age, sex, and BMI among 261 patients
Abbreviation: OR Odds Ratio, CI Confidence Interval, MPV Mean Platelet Volume, CRP C-reactive protein