Table 6.
Patients data according to MPV cutoff value
| Characteristics | MPV > 11.3 fl (n = 55) |
MPV ≤ 11.3 fl (n = 206) |
P |
|---|---|---|---|
| Age, year (mean ± SD) | 72.89 ± 11.64 | 70.79 ± 13.22 | 0.286 |
| Male (n, %) | 36(65.5) | 114(55.3) | 0.178 |
| BMI, kg/m.2(mean ± SD) | 24.29 ± 3.68 | 24.2 ± 4.73 | 0.894 |
| APACHE II score on admission (mean ± SD) | 21.13 ± 6.25 | 18.69 ± 6.98 | 0.019 |
|
IMV duration prior to weaning, days [median(25th–75th percentiles)] |
4(2–9) | 3.5(2–7) | 0.129 |
|
LOS during ICU, days [median(25th–75th percentiles)] |
17(9–28) | 10(3–20) | 0.001 |
|
LOS during hospital, days [median(25th–75th percentiles)] |
20(15–37) | 18(13–28) | 0.154 |
| Cause of mechanical ventilation, n (%) | |||
| Exacerbation of chronic respiratory disorders | 11(20) | 41(19.9) | 0.987 |
| Pneumonia | 21(38.2) | 56(27.2) | 0.112 |
| Sepsis | 8(14.5) | 30(14.6) | 0.997 |
| Postoperation | 10(18.2) | 57(27.7) | 0.152 |
| Congestive heart failure | 3(5.5) | 4(1.9) | 0.164 |
| Neurological disease | 2(3.6) | 12(5.8) | 0.741 |
| others | 0(0) | 6(2.9) | 0.348 |
| Comorbidity disease, n (%) | |||
| Hypertension | 30(54.5) | 114(55.3) | 0.916 |
| Diabetes Mellitus | 19(34.5) | 55(26.7) | 0.251 |
| Chronic heart disorders | 21(38.2) | 62(30.1) | 0.253 |
| Chronic respiratory disorders | 18(32.7) | 59(28.6) | 0.555 |
| Malignancy | 15(27.3) | 46(22.3) | 0.442 |
| Chronic kidney disease | 7(12.7) | 22(10.7) | 0.668 |
| Cerebrovascular disease | 10(18.2) | 33(16.0) | 0.701 |
| Immunosuppression | 3(5.5) | 1(0.5) | 0.030 |
| Vital signs | |||
| RR, breaths/min | 20(16–24) | 20(16–23) | 0.526 |
| SpO2, % | 98(97–100) | 99(97.7–100) | 0.041 |
| HR, beats/min | 86(75–102) | 86(78–98) | 0.747 |
| SPB, mmHg | 129(116–138) | 130(118–144) | 0.440 |
| Arterial blood gas | |||
| PH | 7.45(7.42–7.48) | 7.45(7.42–7.48) | 0.908 |
| PaCO2, mmHg | 41.9(35–48) | 38(34–45) | 0.076 |
| PaO2,mmHg | 90(76–121) | 96(80.8–125.3) | 0.162 |
| PaO2/FiO2, mmHg | 265.7(220.6–362.5) | 295.3(233.7–295.3) | 0.201 |
| Leukocyte count, × 10.9/L | 9.8(7.6–11.8) | 9.1(6.7–12.5) | 0.613 |
| Platelet count, × 109/L | 152(108–196) | 186(140–254) | 0.001 |
| PDW, % | 15.2(12.7–17.0) | 11.8(10.5–12.9) | 0.000 |
| Larger platelet ratio, % | 38.5(34.6–43.4) | 27.1(20.98–31.43) | 0.000 |
| CRP, mg/L | 72(29–105) | 45.5(18–85) | 0.025 |
Continuous variables were presented as median and interquartile range (IQR) or (mean ± standard deviation, SD). Categorical variables were presented as numbers
(n) and percentages (%). Difference of sex, cause of mechanical ventilation, and comorbidity disease between the groups were compared by Chi square (χ2) test. Difference of age, BMI and APACHE II score were compared by Student’s t test. Difference of other variables were compared by Mann–Whitney U-test
Abbreviation: BMI Body Mass Index, APACHE II Acute Physiology And Chronic Health Evaluation II, IMV Invasive Mechanical Ventilation, LOS Length Of Stay, RR Respiratory Rate, HR Heart Rate, SBP Systolic Blood Pressure, SPO2 Peripheral Oxygen Saturation, PaCO2 arterial Carbon Dioxide tension, PaO2 arterial Oxygen tension, FiO2 Fraction of Inspired Oxygen, MPV Mean Platelet Volume, PDW Platelet Distribution Width, CRP C-reactive Protein