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. 2022 May 25;22:580. doi: 10.1186/s12885-022-09597-y

Table 2.

The top 10 genes detected in each cohort

Cohort 1
No. (%)
Cohort 2
No. (%)

No. of patients

N = 26

No. of patients

N = 8

EGFR-L858R 19 (73) EGFR-L858R 3 (37.5)
EGFR-19del 6 (23) EGFR-19del 3 (37.5)
EGFR-L861Q 1 (4) EGFR-20ins 1 (12.5)
EGFR-amp 6 (23) EGFR-L861Q 1 (12.5)
TP53 16 (62) TP53 5 (62.5)
CDKN2A 6 (23) EGFR-amp 4 (50)
CDK4 6 (23) YES1 2 (25)
EGFR-T790M 4 (15) MET 2 (25)
PIK3CG 4 (15) FGF4 1 (12.5)
PIK3CA 3 (12) FGF3 1 (12.5)