Table 1.
Baseline and clinical characteristics of HC and PD participants
| Characteristics | Discovery cohort | Validation cohort | Pa | Pb | ||||
|---|---|---|---|---|---|---|---|---|
| PDa (N = 76) | HCb (N = 76) | p | PDa (N = 80) | HCb (N = 80) | p | |||
| Age (years) | 62.2 ± 7.5 | 60.2 ± 8.2 | 0.14 | 63.7 ± 8.5 | 64.9 ± 8.8 | 0.40 | 0.25 | 0.01 |
| Sex, N | ||||||||
| Female | 38 | 28 | 0.14 | 44 | 39 | 0.43 | 0.63 | 0.15 |
| Male | 38 | 48 | 36 | 41 | ||||
| Disease duration (years) | 4.9 ± 4.3 | / | 3.6 ± 3.6 | / | ||||
| UPDRS I | 8.0 ± 6.1 | / | / | 6.2 ± 4.5 | / | / | 0.05 | / |
| UPDRS II | 11.5 ± 6.8 | / | / | 12.7 ± 6.9 | / | / | 0.28 | / |
| UPDRS III | 28.4 ± 15.1 | / | / | 35.4 ± 18 | / | / | 0.01 | / |
Data are expressed as mean and standard deviation (SD), as appropriate
Pa: comparation of PD participants between discovery and validation cohort; Pb: comparation of HC participants between discovery and validation cohort
PD Parkinson’s disease, UPDRS Unified Parkinson's Disease Rating Scale