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. 2022 May 11;12:884854. doi: 10.3389/fonc.2022.884854

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Copyright © 2022 Wang, Yan, Wang, Yang and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–C) Forest plot of the D* values distinguished wdHCC, mdHCC, and pdHCC. The SMDs indicated that there was no significant difference for grades in HCC. (D) Forest plot of the D* values between MVI- HCC and MVI+ HCC. The SMD indicated that MVI+ HCC had significantly lower D* values than MVI- HCC. wd-HCC, well differentiated hepatocellular carcinoma; md-HCC, moderately differentiated hepatocellular carcinoma; pd-HCC, poorly differentiated hepatocellular carcinoma; MVI, microvascular invasion; SMD, standardized mean difference.