Table I.
Stage I | The carcinoma is strictly confined to the cervix (extension to the corpus should be disregarded) |
IA | Invasive carcinoma that can be diagnosed only by microscopy with a maximum depth of invasion ≤5 mma |
IA1 | Measured stromal invasion ≤3 mm in depth |
IA2 | Measured stromal invasion >3 mm and ≤5 mm in depth |
IB | Invasive carcinoma with measured deepest invasion >5 mm (greater than Stage IA); lesion limited to the cervix uteri with size measured by maximum tumour diameterb |
IB1 | Invasive carcinoma >5 mm depth of stromal invasion and ≤2 cm in greatest dimension |
IB2 | Invasive carcinoma >2 cm and ≤4 cm in greatest dimension |
IB3 | Invasive carcinoma >4 cm in greatest dimension |
Stage II | The cervical carcinoma invades beyond the uterus, but has not extended onto the lower third of the vagina or to the pelvic wall |
IIA | Involvement limited to the upper two-thirds of the vagina without parametrial invasion |
IIA1 | Invasive carcinoma ≤4 cm in greatest dimension |
IIA2 | Invasive carcinoma >4 cm in greatest dimension |
IIB | With parametrial invasion but not up to the pelvic wall |
Stage III | The carcinoma involves the lower third of the vagina and/or extends to the pelvic wall and/or causes hydronephrosis or non-functioning kidney and/or involves pelvic and/or paraaortic lymph nodes |
IIIA | Carcinoma involves lower third of the vagina, with no extension to the pelvic wall |
IIIB | Extension to the pelvic wall and/or hydronephrosis or non-functioning kidney (unless known to be due to another cause) |
IIIC | Involvement of pelvic and/or paraaortic lymph nodes (including micrometastases)c, irrespective of tumour size and extent (with r and p notations)d |
IIIC1 | Pelvic lymph node metastasis only |
IIIC2 | Paraaortic lymph node metastasis |
Stage IV | The carcinoma has extended beyond the true pelvis or has involved (biopsy proven) the mucosa of the bladder or rectum. A bullous oedema, as such, does not permit a case to be allotted to Stage IV |
IVA | Spread of the growth to adjacent organs |
IVB | Spread to distant organs |
Source: Reproduced with permission from Ref 65. aImaging and pathology can be used, when available, to supplement clinical findings with respect to tumour size and extent, in all stages, pathological findings supercede imaging and clinical findings; bThe involvement of vascular/lymphatic spaces should not change the staging. The lateral extent of the lesion is no longer considered; cIsolated tumour cells do not change the stage, but their presence should be recorded. dAdding notation of r (imaging) and p (pathology) to indicate the findings used to allocate the case to stage IIIC.