Table I.

Comparative analysis of genotypic and allelic frequency of interleukin-6-174 G/C (rs1800795) in the study participants

Cytokine loci	Geno types	Frequency (%)			group I vs. group II					group I vs. group III					group II vs. group III
		CaCx cases (group I, n=111)	HPV positive (group II, n=87)	Control (group III, n=163)	Fisher’s two-tailed P values	RR	95% CI	OR	95% CI	Fisher’s two-tailed P values	RR	95% CI	OR	95% CI	Fisher’s two-tailed P values	RR	95% CI	OR	95% CI
IL-6-174 G/C (rs1800795)	GG	77.5 (86)	73.6 (64)	46.6 (76)	0.6	1.1	0.8-1.6	1.2	0.6-2.5	0	2.4	1.6-3.6	3.9	2.2-7.02	0	2.2	1.4-3.4	3.2	1.7-5.9
	GC	19.8 (22)	24.1 (21)	50.3 (82)	0.5	0.9	0.6-1.2	0.8	0.2-1.6	0	0.4	0.3-0.6	0.2	0.1-0.4	0	0.5	0.3-0.7	0.3	0.2-0.6
	CC	2.7 (3)	2.3 (2)	3.1 (5)	1	1.1	0.3-1.7	1.2	0.2-10.4	1	0.9	0.2-1.9	0.9	0.2-4.3	1	0.8	0.1-2.1	0.7	0.1-4.4
	G	87.38 (194)	85.6 (149)	71.78 (234)	0.7	1.1	0.8-1.5	1.2	0.6-2.2	<0.001	1.9	1.4-2.8	2.7	1.7-4.5	0.001	1.8	1.3-2.7	2.3	1.4-3.9
	C	12.6 (28)	14.4 (25)	28.22 (92)

IL-6, interleukin-6; CI, confidence interval; RR, relative risk; OR, odds ratio; CaCx, cervical cancer; HPV, human papillomavirus