Table II.
Comparison of present observation with Indian reports on genotypic frequency of interleukin-6-174 G/C (rs1800795)
| Population | Genotypes | Reference | ||
|---|---|---|---|---|
|
| ||||
| GG, n (%) | GC, n (%) | CC, n (%) | ||
| CaCx cases (Group I, n=111) | 86 (77.5) | 22 (19.8) | 3 (2.7) | Present study |
| HPV positive cases (Group II, n=87) | 64 (73.6) | 21 (24.1) | 2 (2.3) | |
| Control negative (Group III, n=163) | 76 (46.6) | 82 (50.3) | 5 (3.1) | |
| Total (n=361) | 226 (62.6) | 125 (34.6) | 10 (4.4) | |
| South Indian (n=210) | 151 (71.9) | 53 (25.2) | 6 (2.9) | Bhanoori et al18, 2005 |
| North Indian (n=343) | 172 (50.1) | 120 (35.0) | 51 (14.9) | Kesarwani et al19, 2008 |
| Indian (n=185) | 129 (69.73) | 47 (25.41) | 9 (4.9) | Singh et al11, 2015 |
| North Indian (n=130) | 82 (67.1) | 31 (27.0) | 8 (6.0) | Kaur G et al20, 2007 |
| North Indian (n=569) | 90.5 | 9.3 | 0.2 | Ranganath et al21, 2009 |
| North Indian (n=34) | 59.8 | 33.7 | 6.5 | Rani et al22, 2001 |
| Gujarati Indian from Houston, Texas (n=101, males=58 and females=43) | 76 (75.2) | 24 (23.8) | 1 (0.99) | HapMap 3 Release 3 |
| Males=58 | 46 (79.3) | 11 (18.97) | 1 (1.7) | |
| Females=43 | 30 (69.8) | 13 (30.2) | 0 (0) | |
HPV, human papillomavirus; CaCx, cervical cancer