Table 3.
Clinicopathological characteristics of the patients according to the results of intraoperative methylene blue testing and postoperative anastomotic leaks
|
Variable
|
IMBT group
|
IMBT
|
P
value
|
Control group
|
PAL
|
P
value
|
||
|
Negative
|
Positive (%)
|
Negative
|
Positive (%)
|
|||||
| Cases | 211 | 204 | 7 (3.3) | - | 302 | 289 | 13(4.3) | - |
| Gender | ||||||||
| Male | 130 | 126 | 4 (3.1) | 1.0 | 182 | 173 | 9 (4.9) | 0.575 |
| Female | 81 | 78 | 3 (3.7) | 120 | 116 | 4 (3.3) | ||
| Age (yr) | ||||||||
| < 75 | 143 | 139 | 4 (2.8) | 0.541 | 196 | 191 | 5 (2.6) | 0.70 |
| ≥ 75 | 68 | 65 | 3 (4.4) | 106 | 98 | 8 (7.5) | ||
| BMI (kg/m2) | ||||||||
| < 25 | 155 | 153 | 2 (1.3) | 0.021 | 211 | 206 | 5 (2.4) | 0.025 |
| ≥ 25 | 56 | 51 | 5 (8.9) | 91 | 83 | 8 (8.8) | ||
| Preoperative complications | ||||||||
| Absent | 123 | 120 | 3 (2.4) | 0.454 | 191 | 187 | 4 (2.0) | 0.018 |
| Present | 88 | 84 | 4 (4.5) | 111 | 102 | 9 (8.1) | ||
| Neoadjuvant chemotherapy | ||||||||
| Absent | 168 | 165 | 3 (1.8) | 0.033 | 241 | 234 | 7 (2.9) | 0.028 |
| Present | 43 | 39 | 4 (9.3) | 61 | 55 | 6 (9.8) | ||
| Degree of tumor differentiation | ||||||||
| High | 72 | 70 | 2 (2.8) | 0.784 | 92 | 88 | 4 (4.3) | 1.000 |
| Medium | 95 | 92 | 3 (3.2) | 142 | 136 | 6 (4.2) | ||
| Low | 44 | 42 | 2 (4.5) | 68 | 65 | 3 (4.6) | ||
| Postoperative tumor pathological stage1 | ||||||||
| I | 32 | 30 | 2 (6.3) | 0.493 | 62 | 59 | 3 (4.8) | 0.754 |
| II | 62 | 60 | 2 (3.2) | 94 | 89 | 5 (5.3) | ||
| III | 117 | 114 | 3 (2.6) | 146 | 141 | 5 (3.4) | ||
1
According to the 8th AJCC TNM staging system for gastric cancer. IMBT: Intraoperative methylene blue testing; PAL: Postoperative anastomotic leak; BMI: Body mass index.