VA.

T site other than glottic larynx.

	LRFS			DSS			OS			DFS
	HR	p	95% CI	HR	p	95% CI	HR	p	95% CI	HR	p	95% CI
Nearest microscopic margin on the specimen (mm) as continuous	0.82*	0.057	0.68-1.00
Frankly infiltrated margin HE sect				2.26**	0.043	1.02-4.96
Grading (continuous)							1.65^	0.008	1.14-2.40
TNM stage (III-IV vs I-II)							2.79^	0.009	1.29-6.00
pT (classes 3-4 vs classes 1-2)				2.43**	0.017	1.17-5.07	1.91^	0.035	1.05-3.48	1.80°	0.054	0.99-3.27
Pathologic lymph nodes with ECS (at least 1 vs none)	2.3*	0.039	1.04-5.08	2.07**	0.046	1.01-4.24				2.03°	0.019	1.12-3.66

^* Adjusted by: previous treatment, fresh specimen evaluation, nearest microscopic margin on the specimen, grading, lymphovascular invasion, perineural invasion, cT, pT.

^** Adjusted by: previous treatment, nearest microscopic margin on the specimen, depth of invasion, grading, lymphovascular invasion, perineural invasion, cT, cN, pN, identified lymph nodes, chemotherapy.

^{^} Adjusted by: depth of invasion, frankly infiltrated margin HE, nearest microscopic margin on the specimen, lymphovascular invasion, perineural invasion, cT, cN, pN, identified lymph nodes, pathologic lymph nodes with ECS.

^° Adjusted by: previous treatment, frankly infiltrated margin HE, nearest microscopic margin on the specimen, grading, lymphovascular invasion, perineural invasion, TNM stage, pN, identified lymph nodes, number of pathological lymph nodes.