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. 2022 May 11;12:878499. doi: 10.3389/fonc.2022.878499

Table 2.

Characteristics of patients with MIBC.

Characteristics No. of patients Good Responder (n = 36) Non-Good Responder (n = 34) P value
Age* (years old, mean ± SD) 61.9 ± 8.3 61.1 ± 9.1 62.8 ± 7.4 0.39
Gender
 Male 62 30 (83%) 32 (94%) 0.30
 Female 8 6 (17%) 2 (6%)
Number of lesions 0.99
 Solitary 48 24 (64%) 24 (60%)
 Multiple 22 12 (36%) 10 (40%)
Clinical T stage (cT) 0.004
 cT2 21 17 (55%) 4 (28%)
 cT3 43 17(39%) 26 (64%)
 cT4a 6 2 (6%) 4 (8%)
Histological grade 0.28
 Low grade 14 9 (36%) 5 (36%)
 High grade 56 27 (64%) 29 (64%)
NAC courses 0.38
 2 18 7 (19%) 11 (32%)
 3 32 19 (53%) 13 (38%)
 4 20 10 (28%) 10 (30%)
Surgery N/A
 Radical cystectomy + PLND 23 1 (12%) 22 (60%)
 Partial cystectomy + PLND 9 3 (21%) 6 (12%)
 TURBT+CRT 38 32 (67%) 6 (28%)
Pathological Stages (pT) N/A
 pT0 2 2 (5%)
 pTa 1 1 (3%)
 pTis 1 1 (3%)
 pT1 32 32 (89%)
 pT2 13 13 (38%)
 pT3 15 15 (44%)
 pT4 6 6 (18%)

Except where indicated, data include number of participants, with percentages in parentheses. SD, standard deviation, MIBC,muscle-invasive bladder cancer; TURBT,transurethral resection of bladder tumor; NAC,neoadjuvant chemotherapy; CRT, chemoradiotherapy; PLND,pelvic lymphadenectomy; N/A,not applicable; RC, radical cystectomy.

*Data are presented as mean ± standard deviation.