Table 2.
Characteristics | No. of patients | Good Responder (n = 36) | Non-Good Responder (n = 34) | P value |
---|---|---|---|---|
Age* (years old, mean ± SD) | 61.9 ± 8.3 | 61.1 ± 9.1 | 62.8 ± 7.4 | 0.39 |
Gender | ||||
Male | 62 | 30 (83%) | 32 (94%) | 0.30 |
Female | 8 | 6 (17%) | 2 (6%) | |
Number of lesions | 0.99 | |||
Solitary | 48 | 24 (64%) | 24 (60%) | |
Multiple | 22 | 12 (36%) | 10 (40%) | |
Clinical T stage (cT) | 0.004 | |||
cT2 | 21 | 17 (55%) | 4 (28%) | |
cT3 | 43 | 17(39%) | 26 (64%) | |
cT4a | 6 | 2 (6%) | 4 (8%) | |
Histological grade | 0.28 | |||
Low grade | 14 | 9 (36%) | 5 (36%) | |
High grade | 56 | 27 (64%) | 29 (64%) | |
NAC courses | 0.38 | |||
2 | 18 | 7 (19%) | 11 (32%) | |
3 | 32 | 19 (53%) | 13 (38%) | |
4 | 20 | 10 (28%) | 10 (30%) | |
Surgery | N/A | |||
Radical cystectomy + PLND | 23 | 1 (12%) | 22 (60%) | |
Partial cystectomy + PLND | 9 | 3 (21%) | 6 (12%) | |
TURBT+CRT | 38 | 32 (67%) | 6 (28%) | |
Pathological Stages (pT) | N/A | |||
pT0 | 2 | 2 (5%) | ||
pTa | 1 | 1 (3%) | ||
pTis | 1 | 1 (3%) | ||
pT1 | 32 | 32 (89%) | ||
pT2 | 13 | 13 (38%) | ||
pT3 | 15 | 15 (44%) | ||
pT4 | 6 | 6 (18%) |
Except where indicated, data include number of participants, with percentages in parentheses. SD, standard deviation, MIBC,muscle-invasive bladder cancer; TURBT,transurethral resection of bladder tumor; NAC,neoadjuvant chemotherapy; CRT, chemoradiotherapy; PLND,pelvic lymphadenectomy; N/A,not applicable; RC, radical cystectomy.
*Data are presented as mean ± standard deviation.