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. 2022 May 9;2022(5):CD012809. doi: 10.1002/14651858.CD012809.pub2
Class WHO functional classification for pulmonary hypertension
I Patients with pulmonary hypertension but without resulting limitations of physical activity. Ordinary physical activity does not cause undue fatigue or dyspnoea, chest pain, or heart syncope.
II Patients with pulmonary hypertension resulting in slight limitation of physical activity. They are comfortable at rest. Ordinary physical activity results in undue fatigue or dyspnoea, chest pain, or heart syncope.
III Patients with pulmonary hypertension resulting in marked limitation of physical activity. They are comfortable at rest. Less‐than‐ordinary physical activity causes undue fatigue or dyspnoea, chest pain, or heart syncope.
IV Patients with pulmonary hypertension resulting in inability to carry on any physical activity without symptoms. These patients manifest signs of right‐heart failure. Dyspnoea or fatigue, or both, may be present even at rest. Discomfort is increased by physical activity.