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. 2022 Apr 1;13(5):610–621. doi: 10.1039/d1md00403d

Pharmacokinetic properties of PFD, compound YZQ17 in rats.

Comp. Mode T 1/2 (h) T max (h) C max (ng mL−1) AUC(0−t) (ng h mL−1) AUC(0−∞) (ng h mL−1) MRT(0−t) (h) F%
YZQ17 i.v. a 0.694 0.083 712.46 700.647 701.170 0.856
p.o. b 2.772 1.012 68.495 332.288 406.497 4.837 51%
a

Dose: 2 mg kg−1.

b

Dose: 10 mg kg−1.