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. 2022 May 11;13:897791. doi: 10.3389/fphar.2022.897791

TABLE 1.

IC50 Values of Honokiol on AML cell lines.

Cell lines IC50 (μM) ± SD
24 h 48 h 72 h
THP-1 20.64 ± 2.94 17.64 ± 2.51 13.78 ± 0.86
U-937 36.49 ± 2.36 29.72 ± 2.05 17.85 ± 3.23
SKM-1 32.05 ± 1.3 28.71 ± 1.87 21.07 ± 2.86

IC50 values are calculated from cell proliferation assays. IC50 (μM) ± SD: the compound concentration at which cell survival was inhibited by 50% (means ± SD). Values are representative of three independent experiments, and each experiment was performed in triplicate.