Table 3. The DEGs enriched the pathways related to environmental information processing.

Pathway	DEGs
	Up	Down
Sphingolipid signaling pathway	CTSD, FCER1G, MAP2K2, MAPK11, MAPK12, MAPK13, SMPD1, SPHK1, SPTLC1, TNF	ASAH1, FCER1A, MS4A2, PPP2R1B, PPP2R2B, PPP2R5E
MAPK signaling pathway-fly	DOK2, MAPK11, MAPK12, MAPK13, RASA3	IPO7, LOC101111026, MAP3K7, PTPN11, STRN, TBL1XR1, YWHAZ
Phospholipase D signaling pathway	AGPAT2, AGT, DGKQ, FCER1G, LPAR2, MAP2K2, SPHK1, TSC2	ADCY1, FCER1A, KIT, KITLG, LOC101120590, LPAR3, MS4A2, PTPN11, RRAS2
MAPK signaling pathway	AREG, CACNA1G, CACNB2, EFNA1, EFNA4, HSPA6, HSPB1, MAP2K2, MAPK11, MAPK12, MAPK13, MAPK7, MAPK8IP1, MAPKAPK2, NFKB2, RELB, TNF, VEGFB	CACNA1S, CHUK, DUSP4, FGF1, KIT, KITLG, MAP3K7, PLA2G4F, RPS6KA3, RRAS2
VEGF signaling pathway	HSPB1M, MAP2K2, MAPK11, MAPK12, MAPK13, MAPKAPK2, PLA2G4F, SPHK1
Hippo signaling pathway	AREG, SCRIB, TP73	BMPR1A, BMPR2, CCND1, DLG1, FGF1, FRMD6, MOB1B, MPP5, PPP1CB, PPP2R1B, PPP2R2B, WNT2, YWHAZ
TGF-β signaling pathway	BMPR2, FST, TNF	BMPR1A, INHBA, PPP2R1B, RBL1, SMAD5, THSD4, ZFYVE16