Table 1.
Baseline patient characteristics. All values are number (%) unless stated otherwise. BMI = Body Mass Index, MI = myocardial infarction, PCI = percutaneous coronary intervention.
| Non-COVID |
COVID |
p-Value | |
|---|---|---|---|
| n = 365 | n = 101 | ||
| Age (mean ± SD) | 59.2.7 (11.6) | 60.5 (11.8) | 0.824 |
| Male sex | 297 (81.4%) | 84 (83.2%) | 0.658 |
| Black, Asian, Minority Ethnic | 176 (48.2%) | 51 (50.5%) | 0.289 |
| Median BMI (IQR) | 27.44 (24.8–28.5) | 26.9 (25.1–29.7) | 0.598 |
| Past medical history | |||
| Hypertension | 150 (41.1%) | 67 (66.3%) | 0.028⁎ |
| Hypercholesterolemia | 148 (40.5%) | 58 (57.4%) | 0.049⁎ |
| Diabetes mellitus | 112 (30.7%) | 46 (45.5%) | 0.048⁎ |
| Smoking history | 188 (51.5%) | 60 (59.4%) | 0.095 |
| Previous MI | 37 (10.1%) | 13 (12.9%) | 0.278 |
| Previous PCI | 61 (16.7%) | 20 (19.8)% | 0.116 |
| STEMI presentation: | |||
| ECG presentation | 0.815 | ||
| Anterior/LBBB | 216 (59.2%) | 63 (62.3%) | – |
| Inferior | 106 (29.0%) | 31 (30.7%) | – |
| Lateral | 22 (6.0%) | 4 (4.0%) | – |
| Posterior | 21 (5.8%) | 3 (3.0%) | |
| Cardiac arrest | 18 (4.9%) | 11 (10.9%) | 0.369 |
| Cardiogenic shock | 49 (13.4%) | 15 (14.8%) | 0.458 |
| Intubated | 36 (9.9%) | 12 (11.9%) | 0.312 |
| Procedural details | |||
| Coronary intervention | 358 (98.0%) | 98 (97.0%) | 1.000 |
| Culprit vessel | 0.789 | ||
| LMS | 7 (1.9%) | 2 (2.0%) | – |
| LAD | 218 (59.7%) | 61 (60.4%) | – |
| Cx | 27 (7.4%) | 9 (8.9%) | – |
| RCA | 113 (31.0%) | 29 (28.7%) | – |
| Multi-vessel thrombosis | 26 (7.1%) | 16 (15.8%) | 0.041⁎ |
| Stent thrombosis – no. (%) | 8 (2.2%) | 13 (12.9%) | 0.007⁎⁎ |
| Stent type | 0.567 | ||
| Xience | 271 (75.7%) | 73 (74.5%) | |
| Promus | 70 (19.6%) | 20 (20.4%) | |
| Synergy | 17 (4.7%) | 5 (5.1%) | |
| Heparin dose IQR | 10,450 | 9950 | 0.438 |
| Type of P2Y12 | 0.634 | ||
| Ticagrelor | 252 (69.0%) | 72 (71.3%) | |
| Clopdiogrel | 73 (20.0%) | 20 (19.8%) | |
| Prasugrel | 40 (11.0%) | 9 (8.9%) | |
| Baseline TIMI flow 0–1 | 287 (78.6%) | 85 (84.2%) | 0.887 |
| Baseline thrombus grade (4-5) | 281 (77.0%) | 87 (86.1%) | 0.522 |
| Modified thrombus grade (4-5) | 143 (39.2%) | 70 (69.3%) | 0.008⁎⁎ |
| GP IIb/IIIa inhibitor use | 34 (9.3%) | 60 (59.4%) | <0.0001⁎⁎⁎ |
| Aspiration thrombectomy use | 5 (1.4%) | 18 (17.8%) | 0.0021⁎⁎ |
| Procedural success: | |||
| Post PCI TIMI 3 flow | 344 (96.1%) | 91 (92.9)% | 0.687 |
| Median LV ejection fraction (IQR) | 47 (42–51) | 43.8 (33–46) | 0.017⁎ |
⁎
P < 0.05.
⁎⁎
P < 0.01.
⁎⁎⁎
P < 0.0001.