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. 2022 May 24;60(1):846–853. doi: 10.1080/13880209.2022.2066700

Figure 5.

Figure 5.

The effects of EMS on expression of miRNA-33/NLRP3 in the PMs of AA rats. miRNA-33, NLRP3, ASC and caspase-1 mRNAs were detected by RT-qPCR. (A) mRNA levels of miRNA-33, NLRP3, ASC and caspase-1. The effects of EMS on the expression of NLRP3 inflammasome-associated protein in the PMs of AA rats. (B) The protein levels of NLRP3, ASC, caspase-1, pro-caspase-1 were determined by western blotting. Densitometric analyses of the NLRP3 inflammasome-associated protein normalized to histone β-actin. (C) ASC, (D) caspase-1, (E) NLRP3 and (F) pro-caspase-1. ##p < 0.01, vs. the normal group; **p < 0.01 vs. the model group (n = 3).