Fig. 4. (a–f) Cytotoxicity tests of (a) CNPs, (b) Sil, (c) Sil–CNPs composite on Vero cells, (d–f) cytotoxicity of (d) CNPs, (e) Sil, and (f) Sil–CNPs composite on Vero E6 cells. Cellular uptake of (g) CNPs, and (h) Sil–CNPs using TEM after 24 h cell exposure. *CNPs: chitosan nanoparticles, Sil–CNPs: silymarin–chitosan nanoparticles, NM: nuclear membrane, and CYT: cytoplasm. These figures (a–f) were replaced by CC50 instead of IC50.
