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. 2021 Jan 20;106(6):831–838. doi: 10.1136/bjophthalmol-2020-318286

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Analysis of prediction factors. (A) Correlation of age and the improvement of the dark-adapted threshold in dB as measured by the FST with blue stimuli. Grey: data from 1 month after treatment, black: data from 3 months after treatment. (B) Correlation of age and the improvement of the dark-adapted threshold in dB expressed as the average sensitivity change in the 15 degrees macular region measured by DAC cyan stimuli. Grey: data from 1 month after treatment, black: data from 3 months after treatment. (C) Correlation of age and the improvement of the pupil reaction to the scotopic CPC stimuli expressed as the average improvement of the relMCA in % in 15 degrees macular region. Grey: data from 1 month after treatment, black: data from 3 months after treatment. (D) Correlation of the retinal volume evaluated in four quadrants of 3–12 degrees eccentricity (superior, nasal, inferior, lateral) and the averaged relMCA in corresponding retinal locations. Grey: data from 1 month after treatment, black: data from 3 months after treatment. (E) Correlation of the retinal volume evaluated in four quadrants of 3–12 degrees eccentricity (superior, nasal, inferior, lateral) and the improvement of the dark-adapted sensitivity in dB expressed as the average threshold change in the 15 degrees macular region measured by DAC with cyan stimuli. Grey: data from 1 month after treatment, black: data from 3 months after treatment. CPC, chromatic pupil campimetry; DAC, dark-adapted chromatic perimeter; FST, full-field stimulus threshold; OCT, optical coherence tomography; relMCA, relative maximal constriction amplitude.