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. 2021 Jan 20;106(6):831–838. doi: 10.1136/bjophthalmol-2020-318286

Table 2.

Functional readouts of the treated patients’ eyes

ID P1 P1 P2 P3 P4 P4 P8 Average
Eye RE LE LE LE RE LE LE
BCVA
Baseline 0.125 0.16 0.025 0.06 FC FC 0.2
Month 1 0.125 0.16 0.025 0.1 0.025 0.03 0.2
Month 3 0.2 0.1 0.025 0.125 0.02 0.02 0.25
FST blue (dB) Baseline −0.83 −9.71 0.22 −0.72 −4.15 −0.91 −7.60 −3.39
Month 1 −26.20 −18.84 −11.11 −44.00 −2.06 −5.55 −34.73 −20.36
Month 3 −18.77 −25.69 −6.29 −29.10 −6.07 −6.83 −23.44 −16.60
FST red (dB) Baseline 1.5 −1.93 3.7 0.85 3.18 2.73 −4.21 0.83
Month 1 −7.72 −9.1 −0.48 −18.68 4.85 −6.09 −10.88 −6.87
Month 3 −11.05 −7.02 1.96 −9.56 −0.23 1.58 −6.49 −4.40
DAC blue average (dB) Baseline −1.10 0.00 0.00 −1.40 0.00 −2.70 −15.20 −2.91
Month 1 −18.50 −14.80 −0.60 −25.40 0.00 −0.50 −21.60 −11.63
Month 3 −21.90 −18.70 0.00 −28.40 0.00 0.00 −24.00 −13.29
DAC red average (dB) Baseline 0.00 −0.75 0.00 −3.20 0.00 0.00 −3.10 −1.01
Month 1 −4.20 −2.20 0.00 −14.10 0.00 0.00 −6.30 −3.83
Month 3 −5.20 −3.20 0.00 −12.90 0.00 0.00 −5.80 −3.87
CPC rods average (relMCA) Baseline 0.00 0.21 0.06 0.00 0.41 0.59 0.89 0.31
Month 1 1.07 1.18 0.06 2.58 0.48 0.71 4.61 1.53
Month 3 2.00 0.32 0.00 3.52 0.35 0.41 4.07 1.52
CPC cones average
(relMCA)
Baseline 5.40 1.27 0.37 4.60 4.30 4.88 8.03 4.12
Month 1 6.37 4.62 3.92 14.75 4.91 3.34 8.37 6.61
Month 3 4.20 5.12 0.90 14.00 4.41 5.03 5.54 5.60

The functional readouts of the treated eyes are shown for the baseline, 1 month and 3 months after the injection. BCVA is shown in decimal values. FST is shown in dB (0 dB=0.01 cd/m2). DAC values show the average sensitivity in the 15 degrees macular area, representing the treated region (0 dB=17.6 cd/m2). CPC values show the average relative maximal constriction amplitude (relMCA) in 15 degrees macular area, representing the treated region.

BCVA, best corrected visual acuity; CPC, chromatic pupil campimetry; DAC, dark-adapted chromatic perimeter; FC, finger counting; FST, full-field stimulus threshold; LE, left eye; RE, right eye.