Table 2.
ID | P1 | P1 | P2 | P3 | P4 | P4 | P8 | Average | |
Eye | RE | LE | LE | LE | RE | LE | LE | ||
BCVA |
Baseline | 0.125 | 0.16 | 0.025 | 0.06 | FC | FC | 0.2 | |
Month 1 | 0.125 | 0.16 | 0.025 | 0.1 | 0.025 | 0.03 | 0.2 | ||
Month 3 | 0.2 | 0.1 | 0.025 | 0.125 | 0.02 | 0.02 | 0.25 | ||
FST blue (dB) | Baseline | −0.83 | −9.71 | 0.22 | −0.72 | −4.15 | −0.91 | −7.60 | −3.39 |
Month 1 | −26.20 | −18.84 | −11.11 | −44.00 | −2.06 | −5.55 | −34.73 | −20.36 | |
Month 3 | −18.77 | −25.69 | −6.29 | −29.10 | −6.07 | −6.83 | −23.44 | −16.60 | |
FST red (dB) | Baseline | 1.5 | −1.93 | 3.7 | 0.85 | 3.18 | 2.73 | −4.21 | 0.83 |
Month 1 | −7.72 | −9.1 | −0.48 | −18.68 | 4.85 | −6.09 | −10.88 | −6.87 | |
Month 3 | −11.05 | −7.02 | 1.96 | −9.56 | −0.23 | 1.58 | −6.49 | −4.40 | |
DAC blue average (dB) | Baseline | −1.10 | 0.00 | 0.00 | −1.40 | 0.00 | −2.70 | −15.20 | −2.91 |
Month 1 | −18.50 | −14.80 | −0.60 | −25.40 | 0.00 | −0.50 | −21.60 | −11.63 | |
Month 3 | −21.90 | −18.70 | 0.00 | −28.40 | 0.00 | 0.00 | −24.00 | −13.29 | |
DAC red average (dB) | Baseline | 0.00 | −0.75 | 0.00 | −3.20 | 0.00 | 0.00 | −3.10 | −1.01 |
Month 1 | −4.20 | −2.20 | 0.00 | −14.10 | 0.00 | 0.00 | −6.30 | −3.83 | |
Month 3 | −5.20 | −3.20 | 0.00 | −12.90 | 0.00 | 0.00 | −5.80 | −3.87 | |
CPC rods average (relMCA) | Baseline | 0.00 | 0.21 | 0.06 | 0.00 | 0.41 | 0.59 | 0.89 | 0.31 |
Month 1 | 1.07 | 1.18 | 0.06 | 2.58 | 0.48 | 0.71 | 4.61 | 1.53 | |
Month 3 | 2.00 | 0.32 | 0.00 | 3.52 | 0.35 | 0.41 | 4.07 | 1.52 | |
CPC cones average (relMCA) |
Baseline | 5.40 | 1.27 | 0.37 | 4.60 | 4.30 | 4.88 | 8.03 | 4.12 |
Month 1 | 6.37 | 4.62 | 3.92 | 14.75 | 4.91 | 3.34 | 8.37 | 6.61 | |
Month 3 | 4.20 | 5.12 | 0.90 | 14.00 | 4.41 | 5.03 | 5.54 | 5.60 |
The functional readouts of the treated eyes are shown for the baseline, 1 month and 3 months after the injection. BCVA is shown in decimal values. FST is shown in dB (0 dB=0.01 cd/m2). DAC values show the average sensitivity in the 15 degrees macular area, representing the treated region (0 dB=17.6 cd/m2). CPC values show the average relative maximal constriction amplitude (relMCA) in 15 degrees macular area, representing the treated region.
BCVA, best corrected visual acuity; CPC, chromatic pupil campimetry; DAC, dark-adapted chromatic perimeter; FC, finger counting; FST, full-field stimulus threshold; LE, left eye; RE, right eye.