Table 3.

The Box-Behnken response surface design and corresponding response values.

Std. order	Run	X1 (ethanol/water %)	X2 (extraction time “hr”)	X3 (material/solvent ratio)	Y1 (yield “gm”)	Y2 ± SD (total phenolic “μg/mg”)
8	1	95.00	48	1:10	2.08	87.72 ± 0.14
10	2	72.50	72	1:20	3.65	93.16 ± 0.14
9	3	72.50	24	1:20	3.20	86.66 ± 0.10
11	4	72.50	24	1:10	2.76	102.27 ± 0.10
2	5	95.00	24	1:15	2.70	64.87 ± 0.14
15	6	72.50	48	1:15	3.22	80.89 ± 0.14
7	7	50.00	48	1:10	3.20	77.63 ± 0.24
6	8	95.00	48	1:20	2.63	56.33 ± 0.14
13	9	72.50	48	1:15	3.32	81.54 ± 0.24
12	10	72.50	72	1:10	2.80	103.65 ± 0.14
17	11	72.50	48	1:15	3.26	87.80 ± 0.14
16	12	72.50	48	1:15	3.29	96.98 ± 0.24
1	13	50.00	24	1:15	3.69	72.76 ± 0.24
3	14	50.00	72	1:15	4.16	77.39 ± 0.24
5	15	50.00	48	1:20	3.90	76.17 ± 0.24
4	16	95.00	72	1:15	2.95	65.28 ± 0.14
14	17	72.50	48	1:15	3.30	80.72 ± 0.14