Table 8.

Effect of optimized extract and indomethacin (10 mg/kg) on carrageenan-induced rat hind paw edema.

	1st hr		2nd hr		3rd hr		4th hr
Groups	Edema%	Inhibition%	Edema%	Inhibition%	Edema%	Inhibition%	Edema%	Inhibition%
Carrageenan	116 ± 10.7	0	147 ± 11.2	0	154 ± 9.0	0	170 ± 7.2	0
Indomethacin	57 ± 2.4*	50.8	68 ± 1.9*	53.7	50 ± 1.6*	67.5	31 ± 1.6*	81.7
200 mg/kg	48 ± 4.6*	58.6	50 ± 1.9*	65.9	49 ± 3.6*	68.18	43 ± 4.2*	74.7
100 mg/kg	52 ± 2.8*	55.17	47 ± 2.9*	68.02	36 ± 2.6*	76.6	28 ± 3.3*	83.5
50 mg/kg	57 ± 5.2*	50.8	53 ± 4.6*	63.9	41 ± 3.7*	73.37	35 ± 2.6*	79.4
25 mg/kg	43 ± 3.9*	62.9	52 ± 5.5*	64.6	45 ± 4.4*	70.77	42 ± 2.2*	75.29

*Statistically significant p < 0.05.