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. 2022 May 25;12:8873. doi: 10.1038/s41598-022-12678-4

Table 1.

Pearson’s r (above the diagonal) and Spearman’s rho (below the diagonal) between the opportunity for selection (Is) and dementia incidence.

All ages 15–49 years old
Dementia incidence Is Ageing GDP PPP Urban Dementia incidence Is Ageing GDP PPP Urban
Dementia incidence 1 − 0.827*** 0.773*** 0.724*** 0.518*** Dementia incidence 1 − 0.857*** 0.752*** 0.793*** 0.555***
Is − 0.830*** 1 − 0.827*** − 0.866*** − 0.594*** Is − 0.861*** 1 − 0.827*** − 0.866*** − 0.594***
Ageing 0.776*** − 0.835*** 1 0.754*** 0.560*** Ageing 0.752*** − 0.827*** 1 0.754*** 0.560***
GDP PPP 0.732*** − 0.877*** 0.767*** 1 0.698*** GDP PPP 0.793*** − 0.866*** 0.754*** 1 0.698***
Urbanization 0.522*** − 0.647*** 0.645*** 0.738*** 1 Urbanization 0.555*** − 0.594*** 0.560*** 0.698*** 1

Significance level: *p < 0.05; **p < 0.01; ***p < 0.001; Sample size range: 175–204.

Data sources: Dementia Incidence expressed as the number of new onsets of Alzheimer's disease and other dementias published by the Institute for Health Metrics and Evaluation (IHME) in 2020; Is measuring the magnitude of the opportunity for natural selection, extracted from the previous publication by You et al. https://doi.org/10.1111/eva.12523; Ageing expressed with life expectancy at 65 years old (2010–2015) published by the United Nations; GDP PPP expressed in purchasing power parity in 2015 US dollars published by the World Bank; Urbanization expressed in percent of population living in urban areas in 2015 published by the World Bank.