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. 2022 May 25;12:8873. doi: 10.1038/s41598-022-12678-4

Table 2.

Comparison of partial correlation coefficients between dementia incidence and each variable when the other three variables were kept statistically constant.

Variables r p r p r p r p
Dementia incidence rate in populations of all ages
Is − 0.429 < 0.001
Ageing 0.278 < 0.001
GDP PPP − 0.018 0.800
Urban < 0.05 0.763
Dementia incidence rate in population segments of 15–49 years old
Is − 0.452 < 0.001
Ageing* NA NA NA NA NA NA NA NA
GDP PPP − 0.160 < 0.05
Urban < 0.01 0.912

Significance level: *p < 0.05; **p < 0.01; ***p < 0.001; sample size range: 170 for all analyses.

Data sources: Dementia Incidence expressed as the number of new onsets of Alzheimer's disease and other dementias published by the Institute for Health Metrics and Evaluation (IHME) in 2020; Is measuring the magnitude of the opportunity for natural selection, extracted from the previous publication by You et al. https://doi.org/10.1111/eva.12523; Ageing expressed with life expectancy at 65 years old (2010–2015) published by the United Nations; GDP PPP expressed in purchasing power parity in 2015 US dollars published by the World Bank; Urbanization expressed in percent of population living in urban areas in 2015 published by the World Bank.