Table 1.

Main characteristics of the patients included in the study and differences between vaccinated and unvaccinated patients.

	Overall (n = 410)	Unvaccinated (n = 201)	Vaccinated (n = 209)	p
Mean age in years (SD; range)	70.7 (13.9; 28–100)	65.6 (14.3)	75.6 (11.6)	<0.001
Age by groups
Under 65	132 (32.2%)	103 (51.2%)	29 (13.9%)	<0.001
Between 65 and 75 years	103 (25.1%)	45 (22.4%)	58 (27.8%)
Between 75 and 85 years	113 (27.6%)	30 (14.9%)	83 (39.7%)
More than 85 years	62 (15.1%)	23 (11.4%)	39 (18.7%)
Sex
Male	202 (49.3%)	101 (50.2%)	101 (48.3%)	0.697
Female	208 (50.7%)	100 (49.8%)	108 (51.7%)
Barthel
> 60	319 (77.8%)	167 (89.8%)	152 (79.2%)	0.004
≤ 60	59 (14.4%)	19 (10.2%)	40 (20.8%)
Not available	32 (7.8%)	–	–
Charlson
<3	232 (78.8%)	176 (87.6%)	147 (70.3%)	<0.001
≥	87 (21.2%)	25 (12.4%)	62 (29.7%)
Comorbidities
Obesity	88 (21.5%)	40 (19.9%)	48 (23%)	0.450
Chronic Respiratory Disease	145 (35.4%)	49 (24.4%)	96 (45.9%)	<0.001
Ischemic heart disease / Heart failure	50 (12.2%)	14 (7%)	36 (17.2%)	0.002
Renal failure	49 (12%)	20 (10%)	29 (13.9%)	0.221
Chronic liver disease	7 (1.7%)	4 (2%)	3 (1.4%)	0.719
Hematologic malignancy	9 (2.2%)	4 (2%)	5 (2.4%)	0.999
Other neoplasms	60 (7.3%)	12 (6%)	18 (8.6%)	0.304
Diabetes	109 (26.6%)	37 (18.4%)	72 (34.4%)	<0.001
HBP	256 (62.4%)	106 (52.7%)	150 (71.8%)	<0.001
Cognitive impairment	49 (12%)	16 (8%)	33 (15.8%)	0.015
Other neurological diseases	96 (23.4%)	41 (20.4%)	55 (26.3%)	0.157
Depressive syndrome	61 (14.9%)	27 (13.4%)	34 (16.3%)	0.420
Heart failure on admission	20 (4.9%)	6 (3%)	14 (6.7%)	0.081
Cardiovascular event during admission	6 (1.5%)	Twenty-one%	4 (1.9%)	0.686
Immunosuppressive treatment	14 (3.4%)	6 (3%)	8 (3.8%)	0.639
Institutionalized	32 (7.8%)	10 (5%)	22 (10.5%)	0.036
ICU admission	24 (5.9%)	18 (9%)	6 (2.9%)	0.009
In-hospital death	142 (34.6%)	49 (24.4%)	93 (44.5%)	<0.001