TABLE 2.
Dilution rate (D, h−1) | Residual lactose concn (S, g/liter) | Succinic acid production (P, g/liter) | Productivity (PD, g/liter/h) | Base dilution factor (%)b | Overall succinate yield (%) |
---|---|---|---|---|---|
0.085 | 9.0 | 24.0 | 2.1 | 8.0 | 72.0 |
0.15 | 11.0 | 19.8 | 3.0 | 11.0 | 64.0 |
The concentrations of lactose and NaCO3 in the feed stream were 45 and 5 g/liter, respectively. The culture vessel was continuously gassed with carbon dioxide (0.15 [vol/vol/min]). The results represent the means of 20 resident times after reaching steady-state conditions.
Relative volume of 2 N NaOH through the pH 6.2 control system.