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. 2022 May 25;12:8862. doi: 10.1038/s41598-022-12806-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Colonisation assessment of S. boulardii in two different mouse strains receiving antibiotic-treatment. (a) A graphical scheme of the study design. The mice were orally administered ~ 10⁸ cells of S. boulardii daily for five successive weeks, with weekly faecal collection. (b) The time-course of log₁₀ mean CFU/g of S. boulardii ± SEM over time (weeks) in faeces from C57BL/6 mice. (c) The time-course of log₁₀ mean CFU/g of S. boulardii ± SEM over time (weeks) in faeces from ob/ob mice. (d) Bar plot of the mean CFU/g assessed in the faeces over the same period. Each dot represents the log₁₀ CFU/g S. boulardii in one mouse.