Table 1:
Socio-demographic and pre-morbid characteristics of women with stages I-III breast cancer in the SABCHO cohort by HIV status
| HIV negative | HIV positive | Total | P-value | |
|---|---|---|---|---|
| HIV status (row %) | 1868 (78.9%) | 499 (21.1%) | 2367 (100.0%) | |
| Age at diagnosis in years | ||||
| <40 | 198 (10.6) | 128 (25.7) | 326 (13.8) | <0.001 |
| 40–49 | 359 (19.2) | 209 (41.9) | 568 (24.0) | |
| 50–59 | 441 (23.6) | 116 (23.2) | 557 (23.5) | |
| 60–69 | 463 (24.8) | 36 (7.2) | 499 (20.1) | |
| ≥70 | 407 (21.8) | 10 (2.0) | 417 (17.6) | |
| a Age at diagnosis in years, Median (IQR) | 58.8 (48.0–68.3) | 45.0 (39.6–52.4) | 55.1 (44.8–65.8) | <0.001 |
| Menopausal status | ||||
| Premenopausal | 543 (29.1) | 308 (61.7) | 851 (36.0) | <0.001 |
| Menopausal | 1325 (70.9) | 191 (38.3) | 1516 (64.0) | |
| Ethnicity | ||||
| Black | 1358 (72.7) | 487 (97.6) | 1845 (77.9) | <0.001 |
| Asian | 245 (13.1) | 2 (0.4) | 247 (10.4) | |
| White | 172 (9.2) | 0 (0.0) | 172 (7.3) | |
| Mixed race | 93 (5.0) | 10 (2.0) | 103 (4.4) | |
| Highest level of education | ||||
| Primary education and below | 558 (30.2) | 101 (20.8) | 659 (28.2) | <0.001 |
| Secondary education and above | 1292 (69.8) | 393 (79.2) | 1685 (71.8) | |
| Wealth index | ||||
| 1 | 313 (16.8) | 158 (31.7) | 471 (19.9) | <0.001 |
| 2 | 347 (18.6) | 130 (26.1) | 477 (20.2) | |
| 3 | 381 (20.4) | 93 (18.6) | 474 (20.0) | |
| 4 | 413 (21.1) | 64 (12.8) | 477 (20.2) | |
| 5 (Wealthiest) | 414 (22.2) | 54 (10.8) | 468 (19.8) | |
| Alcohol | ||||
| Yes | 342 (18.4) | 120 (24.1) | 462 (19.6) | 0.004 |
| No | 1521 (81.6) | 377 (75.9) | 1898 980.4) | |
| Smoking | ||||
| Yes | 265 (14.2) | 41 (8.3) | 306 (13.0) | <0.001 |
| No | 1598 (85.8) | 456 (91.7) | 2054 (87.0) | |
| Body mass index (BMI) | ||||
| <25 | 280 (15.8) | 131 (27.4) | 411 (18.2) | <0.001 |
| 25–29.9 | 457 (25.7) | 138 (28.9) | 595 (26.4) | |
| ≥30 | 1038 (58.5) | 209 (43.7) | 1247 (55.3) | |
| Diabetes | ||||
| Yes | 300 (16.1) | 21 (4.2) | 321 (13.6) | <0.001 |
| No | 1563 (83.9) | 476 (95.8) | 2039 (86.4) | |
| Hypertension | ||||
| Yes | 871 (46.8) | 106 (21.3) | 977 (41.4) | <0.001 |
| No | 992 (53.2) | 391 (78.7) | 1383 (58.6) | |
| Cerebrovascular disease | ||||
| Yes | 137 (7.4) | 10 (2.0) | 147 (6.2) | <0.001 |
| No | 1726 (92.6) | 487 (98.0) | 2213 (93.8) | |
| b ECOG PS | ||||
| 0 & 1 | 1738 (93.3) | 484 (97.2) | 2222 (94.1) | 0.001 |
| 2–4 | 125 (6.7) | 14 (2.8) | 139 (5.9) | |
| Hospitals | ||||
| c CHBAH | 699 (37.4) | 225 (45.1) | 924 (39.0) | <0.001 |
| d CMJAH | 503 (26.9) | 101 (20.2) | 604 (25.5) | |
| Durban | 339 (18.1) | 60 (12.0) | 399 (16.9) | |
| Greys | 398 (16.0) | 93 (18.7) | 391 (16.5) | |
| Ngwelezana | 29 (1.6) | 20 (4.0) | 49 (2.1) |
Abbreviations:
a
IQR (Interquartile range),
b
ECOG (Eastern Cooperative Oncology Group) PS (Performance status) at baseline,
c
CHBAH (Chris Hani Baragwanath Academic Hospital),
d
CMJAH (Charlotte Maxeke Johannesburg Academic Hospital). Missing data: Highest level of education (n=23), Alcohol (n=7), Smoking (n=7), BMI (n=114), Diabetes (n=7), hypertension (n=7), cerebrovascular disease (n=7), ECOG (n=6)