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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Stroke. 2022 Jan 28;53(6):1847–1853. doi: 10.1161/STROKEAHA.121.037438

Table 1:

Baseline demographics, comorbidities and clinical severity factors in intracerebral hemorrhage patients with concurrent intraventricular hemorrhage

Demographic factors IVH Expansion
N=135 (27.0%)
No IVH Expansion
N= 365 (73.0%)
P value
Mean age (SD), years 60.5 (11.3) 57.9 (11.2) 0.01
Male (n,%) 64 (47.4) 158 (43.3) 0.41
Race (n,%)
 White 78 (57.8) 174 (47.7)
 Black 37 (27.4) 131 (35.9) 0.02
 Hispanic 19 (14.1) 41 (11.2)
 Other 1 (0.7) 19 (5.2)
Hypertension (n,%) 107 (79.3) 263 (72.1) 0.10
Hyperlipidemia (n,%) 130 (96.3) 355 (97.3) 0.58
Prior anticoagulant use (n,%) 20 (14.8) 29 (7.9) 0.02
Prior antiplatelet use (n,%) 39 (28.9) 89 (24.4) 0.31
Baseline Clinical Factors
Median Glasgow Coma Scale (IQR) 8 (6–10) 10 (7–13) <0.001
Mean systolic blood pressure (SD), mm Hg 193 (35) 195 (39) 0.64
Imaging Factors
*ICH Location (n,%)
 Lobar 13 (10.4) 39 (10.7)
 Deep 107 (79.3) 294 (80.6) 0.86
 Primary IVH 14 (10.4) 32 (8.7)
Thalamic location (n,%) 87 (64.4) 206 (56.4) 0.11
Baseline ICH volume1, mL 8.5 (4.1–14.6) 7.5 (2.8–13.6) 0.39
Baseline IVH volume1, mL 21.2 (11.5–37.3) 25.6 (15.6–40.3) 0.08
Stability ICH volume1, mL 11.2 (5.5–19.6) 6.6 (2.3–12.8) <0.001
Stability IVH volume1, mL 29.7 (16.7–48.5) 20.4 (11.5–31.1) <0.001
End of Treatment ICH volume1, mL 9.6 (2.3–17.5) 5.5 (1.6–11.4) <0.001
End of Treatment IVH volume1, mL 12.8 (6.7–28.1) 7.2 (2.6–14.1) <0.001
ICH expansion (n,%) 64 (47.4) 54 (14.8) <0.001
Time from ictus to stability CT scan, hours1 41.1 (25.2–49.6) 45.1 (28.2–60.0) 0.01
Intraventricular alteplase use (n,%) 63 (48.8) 183 (50.1) 0.84
Withdrawal of care (n,%) 24 (18.6) 35 (9.6) 0.01

Abbreviations: ICH: Intracerebral hemorrhage; IVH: Intraventricular hemorrhage; N: number; mL: milliliters; SD: Standard deviation; IQR: interquartile range; mm Hg: millimeters of mercury

1

values presented as median (interquartile range)

*

6 patients without clear ICH location