Table 1:
Demographic factors | IVH Expansion N=135 (27.0%) |
No IVH Expansion N= 365 (73.0%) |
P value |
---|---|---|---|
Mean age (SD), years | 60.5 (11.3) | 57.9 (11.2) | 0.01 |
Male (n,%) | 64 (47.4) | 158 (43.3) | 0.41 |
Other | 1 (0.7) | 19 (5.2) | |
Hypertension (n,%) | 107 (79.3) | 263 (72.1) | 0.10 |
Hyperlipidemia (n,%) | 130 (96.3) | 355 (97.3) | 0.58 |
Prior anticoagulant use (n,%) | 20 (14.8) | 29 (7.9) | 0.02 |
Prior antiplatelet use (n,%) | 39 (28.9) | 89 (24.4) | 0.31 |
Baseline Clinical Factors | |||
Median Glasgow Coma Scale (IQR) | 8 (6–10) | 10 (7–13) | <0.001 |
Mean systolic blood pressure (SD), mm Hg | 193 (35) | 195 (39) | 0.64 |
Imaging Factors | |||
Primary IVH | 14 (10.4) | 32 (8.7) | |
Thalamic location (n,%) | 87 (64.4) | 206 (56.4) | 0.11 |
Baseline ICH volume1, mL | 8.5 (4.1–14.6) | 7.5 (2.8–13.6) | 0.39 |
Baseline IVH volume1, mL | 21.2 (11.5–37.3) | 25.6 (15.6–40.3) | 0.08 |
Stability ICH volume1, mL | 11.2 (5.5–19.6) | 6.6 (2.3–12.8) | <0.001 |
Stability IVH volume1, mL | 29.7 (16.7–48.5) | 20.4 (11.5–31.1) | <0.001 |
End of Treatment ICH volume1, mL | 9.6 (2.3–17.5) | 5.5 (1.6–11.4) | <0.001 |
End of Treatment IVH volume1, mL | 12.8 (6.7–28.1) | 7.2 (2.6–14.1) | <0.001 |
ICH expansion (n,%) | 64 (47.4) | 54 (14.8) | <0.001 |
Time from ictus to stability CT scan, hours1 | 41.1 (25.2–49.6) | 45.1 (28.2–60.0) | 0.01 |
Intraventricular alteplase use (n,%) | 63 (48.8) | 183 (50.1) | 0.84 |
Withdrawal of care (n,%) | 24 (18.6) | 35 (9.6) | 0.01 |
Abbreviations: ICH: Intracerebral hemorrhage; IVH: Intraventricular hemorrhage; N: number; mL: milliliters; SD: Standard deviation; IQR: interquartile range; mm Hg: millimeters of mercury
values presented as median (interquartile range)
6 patients without clear ICH location