Figure 4.

Deregulation of the genes involved in the reorganization of the extracellular matrix in the HBMECs induced with domain III of TBEV or WNV. Heat maps presenting deregulation of the gene expression involved in various GO biological processes that cause reorganization of extracellular matrix. The intensity of the color indicates the degree of expression level. Range of the logFC is presented in the scale. Gene expression was considered as significant only when the LogFC was beyond ± 1.2, average logCPM (count per million) was > 3, and p-value was < 0.01. An edgeR package was used for statistical analysis of differentially expressed gene. The unshrunk.logFC and false discovery rate (FDR) values for each genes are presented in Supplementary Dataset.