Table 2.
Associations between the risk score and characteristics of HCC patients in training cohort.
| Characteristic | Low-risk group (n = 124) | High-risk group (n = 123) | P value |
|---|---|---|---|
| Age, median (IQR) | 61 (51, 69) | 61 (52, 69) | 0.924 |
| BMI, meidan (IQR) | 25.65 (23.36, 30.12) | 23.42 (20.94, 27.45) | < 0.001 |
| Gender, n (%) | 0.966 | ||
| Female | 38 (30.6%) | 39 (31.7%) | |
| Male | 86 (69.4%) | 84 (68.3%) | |
| Family cancer history, n (%) | 0.736 | ||
| Yes | 38 (35.5%) | 37 (32.5%) | |
| No | 69 (64.5%) | 77 (67.5%) | |
| Race, n (%) | 122 | 119 | 0.360 |
| American Indian or Alaska native | 0 (0%) | 1 (0.8%) | |
| Asian | 56 (45.9%) | 56 (47.1%) | |
| Black or African American | 3 (2.5%) | 7 (5.9%) | |
| White | 63 (51.6%) | 55 (46.2%) | |
| Alcohol consumption, n (%) | 118 | 0.392 | |
| Yes | 38 (32.8%) | 46 (39.0%) | |
| No | 78 (67.2%) | 72 (61.0%) | |
| Hepatitis B, n (%) | 0.224 | ||
| Yes | 41 (35.3%) | 32 (27.1%) | |
| No | 75 (64.7%) | 86 (72.9%) | |
| Hepatitis C, n (%) | 0.533 | ||
| Yes | 18 (15.5%) | 14 (11.9%) | |
| No | 98 (84.5%) | 104 (88.1%) | |
| T stage, n (%) | 0.031 | ||
| T1 | 71 (57.7%) | 51 (41.5%) | |
| T2 | 29 (23.6%) | 30 (24.3%) | |
| T3 | 19 (15.4%) | 35 (28.5%) | |
| T4 | 3 (2.4%) | 7 (5.7%) | |
| TX | 1 (0.8%) | 0 (0%) | |
| N stage, n (%) | 0.945 | ||
| N0 | 85 (68.4%) | 82 (67.2%) | |
| N1 | 1 (0.8%) | 1 (0.8%) | |
| NX | 38 (30.6%) | 39 (32.0%) | |
| M stage, n (%) | 0.711 | ||
| M0 | 91 (73.4%) | 86 (69.9%) | |
| M1 | 1 (0.8%) | 2 (1.6%) | |
| MX | 32 (25.8%) | 35 (28.5%) | |
| Pathologic stage, n (%) | 0.013 | ||
| Stage I | 69 (59.0%) | 49 (42.6%) | |
| Stage II | 28 (23.9%) | 27 (23.5%) | |
| Stage III | 18 (15.4%) | 37 (32.2%) | |
| Stage IV | 2 (1.7%) | 2 (1.7%) | |
| Neoplasm histologic grade, n (%) | < 0.001 | ||
| G1 | 23 (18.9%) | 10 (8.3%) | |
| G2 | 65 (53.3%) | 53 (43.8%) | |
| G3 | 33 (27.0%) | 49 (40.5%) | |
| G4 | 1 (0.8%) | 9 (7.4%) | |
| Child–pugh classification grade, n (%) | 0.787 | ||
| A | 86 (93.5%) | 61 (91.0%) | |
| B | 6 (6.5%) | 6 (9.0%) | |
| Microvascular invasion, n (%) | 0.113 | ||
| Yes | 33 (29.2%) | 39 (40.6%) | |
| None | 80 (70.8%) | 57 (59.4%) |