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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Exp Eye Res. 2022 Apr 4;219:109059. doi: 10.1016/j.exer.2022.109059

Figure 3.

Figure 3

Optineurin domain structure and loss-of function point mutations. OPTN is a 65-kDa hexameric protein and is comprised of 577 amino acids. Loss-of function point mutations in OPTN's domain that have been implicated in patients with POAG.