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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Pregnancy Hypertens. 2022 Feb 19;28:66–73. doi: 10.1016/j.preghy.2022.02.005

Figure 4: Endothelium-dependent methacholine-induced relaxation response (% relaxation of preconstriction) of mesenteric arteries exposed to sEVs.

Figure 4:

See text for details. The figure shows the percent preconstriction remaining after consecutive doses of methacholine (Y-axis), calculated as detailed in Materials and Methods. The data are presented as mean ± SEM, n=4. *denotes p<0.05 for PE vs healthy pregnancy (control), and # denotes p<0.05 for PE vs no EVs, calculated by 2-way repeated measures ANOVA with post hoc Tukey Test for pairwise comparisons.