Table 1.
Clinical characteristics of participants from whom plasma samples were obtained.
| Uncomplicated pregnancy (n=10) | Preeclampsia (n=10) | Non-pregnant (n=10) | |
|---|---|---|---|
| Maternal age (years) | 24 (21,27) | 28 (25,31) | 29 (24,30) |
| Race (n, % Black) | 2 (20%) | 2 (20%) | 2 (20%) |
| Pre-pregnancy BMI (kg/m2) | 28 (24, 34) | 26 (24, 34) | 25 (20, 31) |
| Gestational age at delivery (wks) | 39.7 (39.2, 40.7) | 37.3 (36.0, 41.0) | 39.6 (39.0, 40.8) |
| Gestational age at venipuncture (wks) | 37.4 ± 0.78 | 37.2 ± 1.1 | N/A |
| Third trimester, pre-delivery BP | |||
| Systolic | 122 ± 3** | 148 ± 3* | 108 ± 3# |
| Diastolic | 69 ± 3 | 92 ± 2* | 69 ± 3# |
| Infant weight (grams) | 3538 ± 157 | 2658 ± 238* | 3551 ± 109# |
| Infant birth weight centile | 52 ± 11 | 31 ± 10 | 59 ± 7 |
| Infant sex (n, % female) | 4 (40%) | 6 (60%) | 6 (60%) |
| Postpartum interval (wks) | N/A | N/A | 53 (46-62) |
| Postpartum BP (1 year) | |||
| Systolic | N/A | N/A | 108 ± 2 |
| Diastolic | N/A | N/A | 69 ± 3 |
Continuous data are given as mean ±SEM if normally distributed or median (25th percentile, 75th percentile). Categorical data are given as number (percent). Groups were compared by either the Kruskal-Wallis or Holm-Sidak tests. BMI: Body mass index was prepregnancy or at study visit for nonpregnant subjects (approximately 1 year after the index uncomplicated pregnancy).
*
P≤0.003 Preeclampsia vs. Uncomplicated pregnancy,
**
P<0.003 Uncomplicated pregnancy vs Nonpregnant,
#
P<0.004 Preeclampsia vs. Nonpregnant.
N/A: Not applicable.