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. Author manuscript; available in PMC: 2023 May 24.
Published in final edited form as: Circulation. 2022 Mar 31;145(21):1592–1604. doi: 10.1161/CIRCULATIONAHA.122.059486

Table 2:

Cardiac Structure, Function, and Hemodynamics at Baseline

Cardiac Structure and Function No PVD
(Exercise PVR<1.74)
(n=382)
Latent PVD
(Exercise PVR≥1.74)
(n=188)
p
LVEF (%) 60±8 59±8 0.200
LA volume index (ml/m2) 34±13 (347) 35±17 (172) 0.270
Septal E/e’ ratio 15.1±6.7 (343) 17.6±8.3 (161) 0.001
Mitral regurgitation (trace/mild/mod %) 49/43/8 41/47/12 0.093
TAPSE (cm) 2.1±0.4 (339) 1.9±0.4 (157) <.001
RV volume index (ml/m2) 23±9 (276) 25±11 (117) 0.063
RA volume index (ml/m2) 27±12 (314) 31±15 (145) 0.003
Resting Hemodynamics
Heart rate (bpm) 72±13 (381) 71±12 (188) 0.688
Systolic blood pressure (mmHg) 141±25 (360) 146±29 (174) 0.046
RA pressure (mmHg) 9±4 (378) 10±4 (187) 0.026
PA mean pressure (mmHg) 25±7 (375) 31±8 (187) <.001
PA wedge pressure (mmHg) 18±7 (375) 20±6 (187) 0.001
Cardiac output (l/min) 5.7±2.2 (366) 5.0±1.3 (185) <.001
Pulmonary vascular resistance (WU) 1.4±0.6 (370) 2.3±0.9 (185) <.001
Peak Exercise Hemodynamics
Heart rate (bpm) 101±22 (381) 102±24 (185) 0.622
Systolic blood pressure (mmHg) 158±34 (339) 165±34 (168) 0.036
RA pressure (mmHg) 18±5 (379) 20±7 (186) <.001
PA mean pressure (mmHg) 44±8 (382) 52±10 (188) <.001
PA wedge pressure (mmHg) 35±8 (382) 35±9 (188) 0.672
Cardiac output (l/min) 9.1±2.8 (382) 7.1±2.3 (188) <.001
Pulmonary vascular resistance (WU) 0.98±0.43 (382) 2.76±0.82 (188) <.001